Reaction Details Report a problem with these data
Target
Cytochrome P450 1A2
Ligand
BDBM50554790
Substrate
n/a
Meas. Tech.
ChEMBL_2050737 (CHEMBL4705436)
IC50
>10000±n/a nM
Citation
 Li, F; Liang, X; Jiang, Z; Wang, A; Wang, J; Chen, C; Wang, W; Zou, F; Qi, Z; Liu, Q; Hu, Z; Cao, J; Wu, H; Wang, B; Wang, L; Liu, J; Liu, Q Discovery of ( J Med Chem 63:13973-13993 (2020) [PubMed]  Article 
Target
Name:
Cytochrome P450 1A2
Synonyms:
Cholesterol 25-hydroxylase | Cytochrome P(3)450 | Cytochrome P450 1A | Cytochrome P450 1A2 (CYP1A2) | Cytochrome P450 4 | Cytochrome P450-P3 | CYPIA2 | CP1A2_HUMAN | CYP1A2
Type:
Enzyme
Mol. Mass.:
58423.38
Organism:
Human
Description:
P05177
Residue:
516
Sequence:
MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
  
Inhibitor
Name:
BDBM50554790
Synonyms:
CHEMBL4781849
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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