Reaction Details Report a problem with these data
Target
Ribosyldihydronicotinamide dehydrogenase [quinone]
Ligand
BDBM50118448
Substrate
n/a
Meas. Tech.
ChEMBL_104940 (CHEMBL714719)
Ki
1810±n/a nM
Citation
 Fukatsu, K; Uchikawa, O; Kawada, M; Yamano, T; Yamashita, M; Kato, K; Hirai, K; Hinuma, S; Miyamoto, M; Ohkawa, S Synthesis of a novel series of benzocycloalkene derivatives as melatonin receptor agonists. J Med Chem 45:4212-21 (2002) [PubMed]  Article 
Target
Name:
Ribosyldihydronicotinamide dehydrogenase [quinone]
Synonyms:
Metallothionein-3 | NMOR2 | NQO2 | NQO2_HUMAN | NRH dehydrogenase [quinone] 2 | NRH:quinone oxidoreductase 2 | QR2 | Quinone reductase 2 | Quinone reductase 2 (NQO2) | Ribosyldihydronicotinamide dehydrogenase [quinone]
Type:
Protein
Mol. Mass.:
25917.25
Organism:
Homo sapiens (Human)
Description:
P16083
Residue:
231
Sequence:
MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTLSNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRVLCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFCGFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPIPCTAHWHFGQ
  
Inhibitor
Name:
BDBM50118448
Synonyms:
CHEMBL135946 | N-[2-(6-Hydroxy-indan-1-yl)-ethyl]-propionamide
Type:
Small organic molecule
Emp. Form.:
C14H19NO2
Mol. Mass.:
233.3062
SMILES:
CCC(=O)NCCC1CCc2ccc(O)cc12
Structure:
Search PDB for entries with ligand similarity: