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Target
G-protein coupled receptor 183
Ligand
BDBM50558426
Substrate
n/a
Meas. Tech.
ChEMBL_2063683 (CHEMBL4718936)
EC50
0.032000±n/a nM
Citation
 Deng, X; Sun, S; Wu, J; Kuei, C; Joseph, V; Liu, C; Mani, NS Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability. Bioorg Med Chem Lett 26:4888-4891 (2016) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 183
Synonyms:
GP183_HUMAN | GPR183 | EBI2
Type:
PROTEIN
Mol. Mass.:
41245.79
Organism:
Human
Description:
ChEMBL_108311
Residue:
361
Sequence:
MDIQMANNFTPPSATPQGNDCDLYAHHSTARIVMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSTNLVISDILFTTALPTRIAYYAMGFDWRIGDALCRITALVFYINTYAGVNFMTCLSIDRFIAVVHPLRYNKIKRIEHAKGVCIFVWILVFAQTLPLLINPMSKQEAERITCMEYPNFEETKSLPWILLGACFIGYVLPLIIILICYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFVLCFTPYHVAIIQHMIKKLRFSNFLECSQRHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMRMLKRQVSVSISSAVKSAPEENSREMTETQMMIHSKSSNGK
  
Inhibitor
Name:
BDBM50558426
Synonyms:
CHEMBL4788348
Type:
Small organic molecule
Emp. Form.:
C27H46O3
Mol. Mass.:
418.66
SMILES:
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O)C
Structure:
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