Reaction Details Report a problem with these data
Target
G-protein coupled receptor 183
Ligand
BDBM50558426
Substrate
n/a
Meas. Tech.
ChEMBL_2063685 (CHEMBL4718938)
EC50
0.702000±n/a nM
Citation
 Deng, X; Sun, S; Wu, J; Kuei, C; Joseph, V; Liu, C; Mani, NS Fluoro analogs of bioactive oxy-sterols: Synthesis of an EBI2 agonist with enhanced metabolic stability. Bioorg Med Chem Lett 26:4888-4891 (2016) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 183
Synonyms:
EBV-induced G-protein coupled receptor 2 | Epstein-Barr virus-induced G-protein coupled receptor 2 | GP183_MOUSE | Gpr183 | Ebi2
Type:
PROTEIN
Mol. Mass.:
40205.57
Organism:
Mouse
Description:
ChEMBL_108312
Residue:
357
Sequence:
MANNFTTPLATSHGNNCDLYAHHSTARVLMPLHYSLVFIIGLVGNLLALVVIVQNRKKINSTTLYSMNLVISDILFTTALPTRIAYYALGFDWRIGDALCRVTALVFYINTYAGVNFMTCLSIDRFFAVVHPLRYNKIKRIEYAKGVCLSVWILVFAQTLPLLLTPMSKEEGDKTTCMEYPNFEGTASLPWILLGACLLGYVLPITVILLCYSQICCKLFRTAKQNPLTEKSGVNKKALNTIILIIVVFILCFTPYHVAIIQHMIKMLCSPGALECGARHSFQISLHFTVCLMNFNCCMDPFIYFFACKGYKRKVMKMLKRQVSVSISSAVRSAPEENSREMTESQMMIHSKASNGR
  
Inhibitor
Name:
BDBM50558426
Synonyms:
CHEMBL4788348
Type:
Small organic molecule
Emp. Form.:
C27H46O3
Mol. Mass.:
418.66
SMILES:
C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O)C
Structure:
Search PDB for entries with ligand similarity: