Reaction Details Report a problem with these data
Target
Transmembrane protease serine 2
Ligand
BDBM50424712
Substrate
n/a
Meas. Tech.
ChEMBL_2067903 (CHEMBL4723156)
EC50
1000±n/a nM
Citation
 Choudhry, N; Zhao, X; Xu, D; Zanin, M; Chen, W; Yang, Z; Chen, J Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). J Med Chem 63:13205-13227 (2020) [PubMed]  Article 
Target
Name:
Transmembrane protease serine 2
Synonyms:
Transmembrane protease serine 2 catalytic chain | Serine protease 10 | Transmembrane protease serine 2 non-catalytic chain | TMPS2_HUMAN | TMPRSS2 | PRSS10
Type:
PROTEIN
Mol. Mass.:
53867.70
Organism:
Human
Description:
ChEMBL_760112
Residue:
492
Sequence:
MALNSGSPPAIGPYYENHGYQPENPYPAQPTVVPTVYEVHPAQYYPSPVPQYAPRVLTQASNPVVCTQPKSPSGTVCTSKTKKALCITLTLGTFLVGAALAAGLLWKFMGSKCSNSGIECDSSGTCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWHPVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
  
Inhibitor
Name:
BDBM50424712
Synonyms:
Camostat Mesilate | Foipan | CAMOSTAT
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: