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Target
Translocator protein
Ligand
BDBM50122293
Substrate
n/a
Meas. Tech.
ChEBML_38875
Ki
0.188000±n/a nM
Citation
 Zhang, MR; Maeda, J; Furutsuka, K; Yoshida, Y; Ogawa, M; Suhara, T; Suzuki, K [18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR). Bioorg Med Chem Lett 13:201-4 (2002) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
BZRP | MBR | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor-related protein | Peripheral-type benzodiazepine receptor | TSPO | TSPO_HUMAN
Type:
Enzyme
Mol. Mass.:
18834.74
Organism:
Homo sapiens (Human)
Description:
P30536
Residue:
169
Sequence:
MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE
  
Inhibitor
Name:
BDBM50122293
Synonyms:
CHEMBL401000 | CHEMBL63064 | N-(2,5-Dimethoxy-benzyl)-N-(5-fluoro-2-phenoxy-phenyl)-acetamide | N-(2,5-dimethoxybenzyl)-N-(5-fluoro-2-phenoxyphenyl)-acetamide | N-(2,5-dimethoxybenzyl)-N-(5-fluoro-2-phenoxyphenyl)acetamide
Type:
Small organic molecule
Emp. Form.:
C23H22FNO4
Mol. Mass.:
395.4235
SMILES:
COc1ccc(OC)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: