Reaction Details Report a problem with these data
Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50124557
Substrate
n/a
Meas. Tech.
ChEMBL_122782 (CHEMBL730890)
Ki
150000±n/a nM
Citation
 Silvestri, R; La Regina, G; De Martino, G; Artico, M; Befani, O; Palumbo, M; Agostinelli, E; Turini, P Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B. J Med Chem 46:917-20 (2003) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Amine oxidase [flavin-containing] B | MAO-B | Monoamine oxidase B | Monoamine oxidase type B | AOFB_BOVIN | MAOB | Monoamine oxidase | Monoamine Oxidase Type B (MAO-B)
Type:
PROTEIN
Mol. Mass.:
58428.94
Organism:
Bovine
Description:
ChEMBL_1501478
Residue:
520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWRTMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEVSALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQTGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVYYKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEERLKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTTFLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
  
Inhibitor
Name:
BDBM50124557
Synonyms:
1-Methyl-1H-pyrrole-2-carboxylic acid benzylamide | CHEMBL170635
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
Cn1cccc1C(=O)NCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: