Reaction Details Report a problem with these data
Target
Amine oxidase [flavin-containing] A
Ligand
BDBM15608
Substrate
n/a
Meas. Tech.
ChEMBL_122779 (CHEMBL730887)
Ki
75.0±n/a nM
Citation
 Silvestri, R; La Regina, G; De Martino, G; Artico, M; Befani, O; Palumbo, M; Agostinelli, E; Turini, P Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B. J Med Chem 46:917-20 (2003) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
Amine oxidase [flavin-containing] A | MAO-A | Monoamine oxidase type A | Monoamine oxidase A | AOFA_BOVIN | MAOA | Monoamine oxidase | Monoamine Oxidase Type A (MAO-A)
Type:
PROTEIN
Mol. Mass.:
59764.63
Organism:
Bovine
Description:
ChEMBL_1501477
Residue:
527
Sequence:
MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHVDYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKLRSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADRLAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAEDVPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
  
Inhibitor
Name:
BDBM15608
Synonyms:
CHEMBL353159 | N-Methyl,N-propargyl-1H-pyrrole-2-carboxamide | N-methyl-N-(prop-2-yn-1-yl)-1H-pyrrole-2-carboxamide | pyrrole inhibitor 33
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: