Target
Melatonin receptor type 1A
Ligand
BDBM50125756
Substrate
n/a
Meas. Tech.
ChEMBL_105097 (CHEMBL714104)
Ki
2.05±n/a nM
Citation
 Descamps-François, CYous, SChavatte, PAudinot, VBonnaud, ABoutin, JADelagrange, PBennejean, CRenard, PLesieur, D Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands. J Med Chem 46:1127-9 (2003) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50125756
Synonyms:
CHEMBL14514 | N-[2-(7-{2-[8-(2-Acetylamino-ethyl)-naphthalen-2-yloxy]-ethoxy}-naphthalen-1-yl)-ethyl]-acetamide
Type:
Small organic molecule
Emp. Form.:
C30H32N2O4
Mol. Mass.:
484.5861
SMILES:
CC(=O)NCCc1cccc2ccc(OCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc12
Structure:
Search PDB for entries with ligand similarity: