Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50511590
Substrate
n/a
Meas. Tech.
ChEMBL_2104707 (CHEMBL4813210)
Ki
0.760000±n/a nM
Citation
 Angeli, A; Pinteala, M; Maier, SS; Toti, A; Di Cesare Mannelli, L; Ghelardini, C; Selleri, S; Carta, F; Supuran, CT Tellurides bearing benzensulfonamide as carbonic anhydrase inhibitors with potent antitumor activity. Bioorg Med Chem Lett 45:0 (2021) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50511590
Synonyms:
CHEMBL4587627
Type:
Small organic molecule
Emp. Form.:
C14H15NO2STe
Mol. Mass.:
388.9
SMILES:
[#6]-c1ccccc1[Te;v2][#6]-c1ccc(cc1)S([#7])(=O)=O
Structure:
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