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Target
D(3) dopamine receptor
Ligand
BDBM50568780
Substrate
n/a
Meas. Tech.
ChEMBL_2106810 (CHEMBL4815485)
Ki
0.660693±n/a nM
Citation
 Biselli, S; Bresinsky, M; Tropmann, K; Forster, L; Honisch, C; Buschauer, A; Bernhardt, G; Pockes, S Pharmacological characterization of a new series of carbamoylguanidines reveals potent agonism at the H Eur J Med Chem 214:0 (2021) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
Dopamine D3 receptor | DRD3_HUMAN | DRD3
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Human
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50568780
Synonyms:
Dexpramipexole | (r)-pramipexole
Type:
Small organic molecule
Emp. Form.:
C10H17N3S
Mol. Mass.:
211.33
SMILES:
[H][C@]1(CCc2nc(N)sc2C1)NCCC |r|
Structure:
Search PDB for entries with ligand similarity: