Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM50568914
Substrate
n/a
Meas. Tech.
ChEMBL_2106949 (CHEMBL4815624)
Ki
111±n/a nM
Citation
 Ofori, E; Onyameh, EK; Gonela, UM; Voshavar, C; Bricker, B; Swanson, TL; Eshleman, AJ; Schmachtenberg, JL; Bloom, SH; Janowsky, AJ; Ablordeppey, SY New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263. Eur J Med Chem 214:0 (2021) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin receptor 2C
Type:
PROTEIN
Mol. Mass.:
51820.72
Organism:
Homo sapiens
Description:
ChEMBL_104992
Residue:
458
Sequence:
MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
  
Inhibitor
Name:
BDBM50568914
Synonyms:
CHEMBL4874069
Type:
Small organic molecule
Emp. Form.:
C22H27N3O
Mol. Mass.:
349.4693
SMILES:
O=C(CCCN1CCN(CC1)c1ccccn1)c1ccc2CCCc2c1
Structure:
Search PDB for entries with ligand similarity: