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Target
D(1A) dopamine receptor
Ligand
BDBM50366495
Substrate
n/a
Meas. Tech.
ChEMBL_2113156 (CHEMBL4822006)
Ki
2.8±n/a nM
Citation
 Cordone, P; Namballa, HK; Muniz, B; Pal, RK; Gallicchio, E; Harding, WW New tetrahydroisoquinoline-based D Bioorg Med Chem Lett 42:0 (2021) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | DRD1_HUMAN | DRD1
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Human
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50366495
Synonyms:
CHEMBL1255588 | (+)butaclamol
Type:
Small organic molecule
Emp. Form.:
C25H31NO
Mol. Mass.:
n/a
SMILES:
CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34 |r|
Structure:
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