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Target
D(3) dopamine receptor
Ligand
BDBM50487259
Substrate
n/a
Meas. Tech.
ChEMBL_2113159 (CHEMBL4822009)
Ki
0.860000±n/a nM
Citation
 Cordone, P; Namballa, HK; Muniz, B; Pal, RK; Gallicchio, E; Harding, WW New tetrahydroisoquinoline-based D Bioorg Med Chem Lett 42:0 (2021) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
Dopamine D3 receptor | DRD3_HUMAN | DRD3
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Human
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50487259
Synonyms:
CHEBI:64219 | [3H]NEMONAPRIDE
Type:
Small organic molecule
Emp. Form.:
C21H26ClN3O2
Mol. Mass.:
387.91
SMILES:
C[C@@H]1[C@@H](CCN1Cc2ccccc2)NC(=O)c3cc(c(cc3OC)NC)Cl
Structure:
Search PDB for entries with ligand similarity: