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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM50130262
Substrate
n/a
Meas. Tech.
ChEMBL_2642 (CHEMBL618697)
Ki
3800±n/a nM
Citation
 Grella, B; Teitler, M; Smith, C; Herrick-Davis, K; Glennon, RA Binding of beta-carbolines at 5-HT(2) serotonin receptors. Bioorg Med Chem Lett 13:4421-5 (2003) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52852.05
Organism:
Rattus norvegicus (rat)
Description:
Rat cortex membranes 5-HT2A receptors.
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM50130262
Synonyms:
2,3,4,9-Tetrahydro-1H-beta-carboline | CHEMBL269236 | EN300-119677
Type:
Small organic molecule
Emp. Form.:
C11H12N2
Mol. Mass.:
172.2264
SMILES:
C1Cc2c(CN1)[nH]c1ccccc21
Structure:
Search PDB for entries with ligand similarity: