Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50573242
Substrate
n/a
Meas. Tech.
ChEMBL_2119288 (CHEMBL4828354)
Ki
6964±n/a nM
Citation
 Kwag, R; Lee, J; Kim, D; Lee, H; Yeom, M; Woo, J; Cho, Y; Kim, HJ; Kim, J; Keum, G; Jeon, B; Choo, H Discovery of G Protein-Biased Antagonists against 5-HT J Med Chem 64:13766-13779 (2021) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5HT1A_HUMAN | ADRB2RL1 | 5-hydroxytryptamine receptor 1A (5-HT-1A) | ADRBRL1 | G-21 | 5-HT-1A | 5-HT1A | HTR1A | Serotonin receptor 1A | Dopamine D2 receptor and serotonin 1a receptor
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Human
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50573242
Synonyms:
CHEMBL4868035
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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