Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50573242
Substrate
n/a
Meas. Tech.
ChEMBL_2119289 (CHEMBL4828355)
Ki
>10000±n/a nM
Citation
 Kwag, R; Lee, J; Kim, D; Lee, H; Yeom, M; Woo, J; Cho, Y; Kim, HJ; Kim, J; Keum, G; Jeon, B; Choo, H Discovery of G Protein-Biased Antagonists against 5-HT J Med Chem 64:13766-13779 (2021) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
Serotonin 1D beta receptor | Serotonin Receptor 1B | S12 | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5-HT1B | 5-HT-1B | 5-HT-1D-beta | 5HT1B_HUMAN | HTR1B | HTR1DB | Serotonin (5-HT) receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
43579.17
Organism:
Human
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells
Residue:
390
Sequence:
MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS
  
Inhibitor
Name:
BDBM50573242
Synonyms:
CHEMBL4868035
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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