Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50573242
Substrate
n/a
Meas. Tech.
ChEMBL_2119296 (CHEMBL4828362)
Ki
>10000±n/a nM
Citation
 Kwag, R; Lee, J; Kim, D; Lee, H; Yeom, M; Woo, J; Cho, Y; Kim, HJ; Kim, J; Keum, G; Jeon, B; Choo, H Discovery of G Protein-Biased Antagonists against 5-HT J Med Chem 64:13766-13779 (2021) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
Serotonin Receptor 4 | 5-HT-4 | 5-HT4S | 5-HT4 | Serotonin (5-HT3) receptor | 5-HT4d | 5-hydroxytryptamine receptor 4 | 5-HT4hb | 5-HT4a | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | 5-HT4b | 5-HT4c | 5HT4R_HUMAN | HTR4 | 5-hydroxytryptamine receptor 4 (5-HT4)
Type:
Enzyme
Mol. Mass.:
43767.54
Organism:
Human
Description:
Q13639
Residue:
388
Sequence:
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
  
Inhibitor
Name:
BDBM50573242
Synonyms:
CHEMBL4868035
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: