Reaction Details Report a problem with these data
Target
Interleukin-17A
Ligand
BDBM50573254
Substrate
n/a
Meas. Tech.
ChEMBL_2119335 (CHEMBL4828401)
Kd
110±n/a nM
Citation
 Anzai, H; Terai, T; Wakabayashi-Nakao, K; Noguchi, T; Kumachi, S; Tsuchiya, M; Nemoto, N Interleukin-17A Peptide Aptamers with an Unexpected Binding Moiety Selected by cDNA Display under Heterogenous Conditions. ACS Med Chem Lett 12:1427-1434 (2021) [PubMed]  Article 
Target
Name:
Interleukin-17A
Synonyms:
CTLA8 | Cytotoxic T-lymphocyte-associated antigen 8 | IL-17 | IL17 | IL17A | IL17_HUMAN | il-17a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17511.44
Organism:
Homo sapiens (Human)
Description:
Q16552
Residue:
155
Sequence:
MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
  
Inhibitor
Name:
BDBM50573254
Synonyms:
CHEMBL4872876
Type:
Small organic molecule
Emp. Form.:
C69H99N13O19S2
Mol. Mass.:
1478.73
SMILES:
CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(O)=O |r|
Structure:
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