Reaction Details Report a problem with these data
Target
Probable G-protein coupled receptor 27
Ligand
BDBM87573
Substrate
n/a
Meas. Tech.
ChEMBL_2121597 (CHEMBL4830744)
EC50
3020±n/a nM
Citation
 Pillaiyar, T; Rosato, F; Wozniak, M; Blavier, J; Charles, M; Laschet, C; Kronenberger, T; Müller, CE; Hanson, J Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27. Eur J Med Chem 225:0 (2021) [PubMed]  Article 
Target
Name:
Probable G-protein coupled receptor 27
Synonyms:
GPR27 | GPR27_HUMAN | Probable G-protein coupled receptor 27 | SREB1 | Super conserved receptor expressed in brain 1
Type:
PROTEIN
Mol. Mass.:
39835.29
Organism:
Homo sapiens
Description:
ChEMBL_119640
Residue:
375
Sequence:
MANASEPGGSGGGEAAALGLKLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGAPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGDDEDAPCALEQRPDGAPGALGFLLLLAVVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAVTLLFLLLWGPYVVASYLRVLVRPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPRTTQATHPCDLKGIGL
  
Inhibitor
Name:
BDBM87573
Synonyms:
2,4-Dichloro-N-[4-(pyridin-2-ylsulfamoyl)-phenyl]-benzamide | 2,4-bis(chloranyl)-N-[4-(pyridin-2-ylsulfamoyl)phenyl]benzamide | 2,4-dichloro-N-[4-(2-pyridinylsulfamoyl)phenyl]benzamide | 2,4-dichloro-N-[4-(2-pyridylsulfamoyl)phenyl]benzamide | 2,4-dichloro-N-[4-(pyridin-2-ylsulfamoyl)phenyl]benzamide | MLS001223293 | SMR000612077 | cid_1078173
Type:
Small organic molecule
Emp. Form.:
C18H13Cl2N3O3S
Mol. Mass.:
422.285
SMILES:
Clc1ccc(C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccccn2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: