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Target
Interleukin-17A
Ligand
BDBM50574353
Substrate
n/a
Meas. Tech.
ChEMBL_2122293 (CHEMBL4831440)
IC50
14±n/a nM
Citation
 Sabnis, RW Imidazo[1,2- ACS Med Chem Lett 12:1526-1527 (2021) [PubMed]  Article 
Target
Name:
Interleukin-17A
Synonyms:
CTLA8 | Cytotoxic T-lymphocyte-associated antigen 8 | IL-17 | IL17 | IL17A | IL17_HUMAN | il-17a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17511.44
Organism:
Homo sapiens (Human)
Description:
Q16552
Residue:
155
Sequence:
MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA
  
Inhibitor
Name:
BDBM50574353
Synonyms:
CHEMBL4860250
Type:
Small organic molecule
Emp. Form.:
C24H27F5N8O3
Mol. Mass.:
570.515
SMILES:
CC(C)c1nonc1C(=O)N[C@@H](C1CCC(F)(F)CC1)c1cn2ncc(CN3C[C@H](NC3=O)C(F)(F)F)cc2n1 |r|
Structure:
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