Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM50197883
Substrate
n/a
Meas. Tech.
ChEMBL_2124234 (CHEMBL4833467)
Kd
200±n/a nM
Citation
Yokoyama, T; Kashihara, M; Mizuguchi, M Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors. J Med Chem 64:14344-14357 (2021) [PubMed] Article
More Info.:
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE