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Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM50142481
Substrate
n/a
Meas. Tech.
ChEBML_158328
Ki
3000±n/a nM
Citation
 Elworthy, TR; Kertesz, DJ; Kim, W; Roepel, MG; Quattrocchio-Setti, L; Smith, DB; Tracy, JL; Chow, A; Li, F; Brill, ER; Lach, LK; McGee, D; Yang, DS; Chiou, SS Lactams as EP4 prostanoid receptor subtype selective agonists. Part 1: 2-Pyrrolidinones-stereochemical and lower side-chain optimization. Bioorg Med Chem Lett 14:1655-9 (2004) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
Prostaglandin E2 receptor EP3A subtype (EP3A) | PGE2-R | Prostaglandin E2 receptor EP3 subtype | PGE receptor, EP3 subtype | Prostaglandin E2 receptor EP3 subtype (EP3) | Prostanoid EP3 receptor | Prostaglandin E2 receptor EP3D subtype (EP3D) | PE2R3_HUMAN | PTGER3 | Prostaglandin E2 receptor
Type:
Enzyme
Mol. Mass.:
43335.03
Organism:
Human
Description:
P43115
Residue:
390
Sequence:
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER
  
Inhibitor
Name:
BDBM50142481
Synonyms:
8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid | CHEMBL42027
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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