Reaction Details Report a problem with these data
Target
Beta-1 adrenergic receptor
Ligand
BDBM25771
Substrate
n/a
Meas. Tech.
ChEMBL_2133587 (CHEMBL4843197)
EC50
372±n/a nM
Citation
 Xing, G; Zhi, Z; Yi, C; Zou, J; Jing, X; Yiu-Ho Woo, A; Lin, B; Pan, L; Zhang, Y; Cheng, M 8-Hydroxyquinolin-2(1H)-one analogues as potential β Eur J Med Chem 224:0 (2021) [PubMed]  Article 
Target
Name:
Beta-1 adrenergic receptor
Synonyms:
adrenergic Beta1 | ADRB1_HUMAN | ADRB1 | ADRB1R | Beta-1 adrenoceptor | B1AR | Beta-1 adrenoreceptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
51338.40
Organism:
Human
Description:
P08588
Residue:
477
Sequence:
MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQGLLCCARRAARRRHATHGDRPRASGCLARPGPPPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV
  
Inhibitor
Name:
BDBM25771
Synonyms:
salmeterol xinafoate | 4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)-2-(hydroxymethyl)phenol | Serevent | 1-hydroxy-2-naphthoic acid;4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]-2-methylol-phenol | Aeromax | Salmeterol
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: