Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50149997
Substrate
n/a
Meas. Tech.
ChEMBL_304755 (CHEMBL829353)
Ki
39±n/a nM
Citation
 Heasley, BH; Jarosz, R; Carter, KM; Van, SJ; Lynch, KR; Macdonald, TL A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist. Bioorg Med Chem Lett 14:4069-74 (2004) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:
Enzyme
Mol. Mass.:
40149.72
Organism:
Homo sapiens (Human)
Description:
Q9UBY5
Residue:
353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
  
Inhibitor
Name:
BDBM50149997
Synonyms:
CHEMBL362053 | Phosphoric acid mono-[3-[4-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethoxy)-phenyl]-2-((Z)-(R)-octadec-9-enoylamino)-propyl] ester
Type:
Small organic molecule
Emp. Form.:
C36H57N2O7P
Mol. Mass.:
660.8207
SMILES:
CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1
Structure:
Search PDB for entries with ligand similarity: