Target
Melatonin receptor type 1B
Ligand
BDBM50153436
Substrate
n/a
Meas. Tech.
ChEMBL_303583
Ki
54±n/a nM
Citation
 Sun, LQTakaki, KChen, JIben, LKnipe, JOPajor, LMahle, CDRyan, EXu, C N-[2-[2-(4-Phenylbutyl)benzofuran-4-yl]cyclopropylmethyl]acetamide: an orally bioavailable melatonin receptor agonist. Bioorg Med Chem Lett 14:5157-60 (2004) [PubMed]  Article
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50153436
Synonyms:
1N-[2-[2-(4-phenylbutyl)benzo[b]furan-4-yl]-(1R,2R)-cyclopropylmethyl]-2-methylpropanamide | CHEMBL184562
Type:
Small organic molecule
Emp. Form.:
C26H31NO2
Mol. Mass.:
389.5298
SMILES:
CC(C)C(=O)NC[C@@H]1CC1c1cccc2oc(CCCCc3ccccc3)cc12
Structure:
Search PDB for entries with ligand similarity: