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Target
Cytochrome P450 1A2
Ligand
BDBM50588800
Substrate
n/a
Meas. Tech.
ChEMBL_2188382 (CHEMBL5100464)
IC50
6990±n/a nM
Citation
 Fallot, LB; Suresh, RR; Fisher, CL; Salmaso, V; O'Connor, RD; Kaufman, N; Gao, ZG; Auchampach, JA; Jacobson, KA Structure-Activity Studies of 1 J Med Chem 65:15238-15262 (2022) [PubMed] 
Target
Name:
Cytochrome P450 1A2
Synonyms:
1.14.14.1 | 4.2.1.152 | CYPIA2 | Cholesterol 25-hydroxylase | Cytochrome P450-P2 | Cytochrome P450-P3 | Hydroperoxy icosatetraenoate dehydratase | CP1A2_MOUSE | Cyp1a2 | Cyp1a-2
Type:
PROTEIN
Mol. Mass.:
58196.77
Organism:
Mouse
Description:
ChEMBL_103898
Residue:
513
Sequence:
MAFSQYISLAPELLLATAIFCLVFWMVRASRTQVPKGLKNPPGPWGLPFIGHMLTVGKNPHLSLTRLSQQYGDVLQIRIGSTPVVVLSGLNTIKQALVRQGDDFKGRPDLYSFTLITNGKSMTFNPDSGPVWAARRRLAQDALKSFSIASDPTSASSCYLEEHVSKEANHLVSKLQKAMAEVGHFEPVSQVVESVANVIGAMCFGKNFPRKSEEMLNIVNNSKDFVENVTSGNAVDFFPVLRYLPNPALKRFKTFNDNFVLFLQKTVQEHYQDFNKNSIQDITSALFKHSENYKDNGGLIPEEKIVNIVNDIFGAGFDTVTTAITWSILLLVTWPNVQRKIHEELDTVVGRDRQPRLSDRPQLPYLEAFILEIYRYTSFVPFTIPHSTTRDTSLNGFHIPKERCIYINQWQVNHDEKQWKDPFVFRPERFLTNNNSAIDKTQSEKVMLFGLGKRRCIGEIPAKWEVFLFLAILLQHLEFSVPPGVKVDLTPNYGLTMKPGTCEHVQAWPRFSK
  
Inhibitor
Name:
BDBM50588800
Synonyms:
CHEMBL5190388
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: