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Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50170841
Substrate
n/a
Meas. Tech.
ChEMBL_303206 (CHEMBL829832)
Ki
588±n/a nM
Citation
 Durgam, GG; Virag, T; Walker, MD; Tsukahara, R; Yasuda, S; Liliom, K; van Meeteren, LA; Moolenaar, WH; Wilke, N; Siess, W; Tigyi, G; Miller, DD Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin. J Med Chem 48:4919-30 (2005) [PubMed]  Article 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:
Enzyme
Mol. Mass.:
40149.72
Organism:
Homo sapiens (Human)
Description:
Q9UBY5
Residue:
353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
  
Inhibitor
Name:
BDBM50170841
Synonyms:
CHEMBL191411 | Phosphoric acid mono-[(S)-3-(4-benzyloxy-phenyl)-2-octadecanoylamino-propyl] ester
Type:
Small organic molecule
Emp. Form.:
C34H54NO6P
Mol. Mass.:
603.7694
SMILES:
CCCCCCCCCCCCCCCCCC(=O)N[C@H](COP(O)(O)=O)Cc1ccc(OCc2ccccc2)cc1
Structure:
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