Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50601551
Substrate
n/a
Meas. Tech.
ChEMBL_2237570 (CHEMBL5151466)
Kd
0.025800±n/a nM
Citation
 Tropmann, K; Bresinsky, M; Forster, L; Mönnich, D; Buschauer, A; Wittmann, HJ; Hübner, H; Gmeiner, P; Pockes, S; Strasser, A Abolishing Dopamine D J Med Chem 64:8684-8709 (2021) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
Dopamine D3 receptor | DRD3_HUMAN | DRD3
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Human
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50601551
Synonyms:
CHEMBL5207281
Type:
Small organic molecule
Emp. Form.:
C16H25F6N7O5S
Mol. Mass.:
541.48
SMILES:
CCCCCNC(=O)N=C(/N)NCCCc1nnc(N)s1
Structure:
Search PDB for entries with ligand similarity: