Target
Thromboxane A2 receptor
Ligand
BDBM50184228
Substrate
n/a
Meas. Tech.
ChEMBL_364758
Ki
2.4±n/a nM
Citation
 Sturino, CFLachance, NBoyd, MBerthelette, CLabelle, MLi, LRoy, BScheigetz, JTsou, NBrideau, CCauchon, ECarriere, MCDenis, DGreig, GKargman, SLamontagne, SMathieu, MCSawyer, NSlipetz, DO'Neill, GWang, ZZamboni, RMetters, KMYoung, RN Identification of an indole series of prostaglandin D2 receptor antagonists. Bioorg Med Chem Lett 16:3043-8 (2006) [PubMed]  Article
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50184228
Synonyms:
2-(9-(4-chlorobenzyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid | CHEMBL206631
Type:
Small organic molecule
Emp. Form.:
C21H20ClNO2
Mol. Mass.:
353.842
SMILES:
OC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1ccccc21
Structure:
Search PDB for entries with ligand similarity: