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Target
Galanin receptor type 3
Ligand
BDBM50187908
Substrate
n/a
Meas. Tech.
ChEMBL_384498 (CHEMBL866716)
Ki
27±n/a nM
Citation
 Konkel, MJ; Packiarajan, M; Chen, H; Topiwala, UP; Jimenez, H; Talisman, IJ; Coate, H; Walker, MW Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility. Bioorg Med Chem Lett 16:3950-4 (2006) [PubMed]  Article 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM50187908
Synonyms:
(S)-1-(3-(3-(diethylamino)-2-hydroxypropoxy)phenyl)-3-(3-(trifluoromethyl)phenylimino)indolin-2-one | CHEMBL209642
Type:
Small organic molecule
Emp. Form.:
C28H28F3N3O3
Mol. Mass.:
511.5354
SMILES:
CCN(CC)C[C@H](O)COc1cccc(c1)N1C(=O)\C(=N\c2cccc(c2)C(F)(F)F)c2ccccc12
Structure:
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