Reaction Details Report a problem with these data
Target
Sulfotransferase 1A1
Ligand
BDBM23420
Substrate
n/a
Meas. Tech.
ChEMBL_2281002
IC50
290±n/a nM
Citation
 Tanwar, AK; Dhiman, N; Kumar, A; Jaitak, V Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. Eur J Med Chem 213:0 (2021) [PubMed] 
Target
Name:
Sulfotransferase 1A1
Synonyms:
2.8.2.1 | ASTIV | Aryl sulfotransferase | Aryl sulfotransferase IV | Minoxidil sulfotransferase | Mx-ST | PST-1 | Phenol sulfotransferase | ST1A1 | St1a1 | Sulfokinase | Sulfotransferase 1A1 | Sult1a1 | Tyrosine-ester sulfotransferase
Type:
PROTEIN
Mol. Mass.:
33907.66
Organism:
Rat
Description:
ChEMBL_10115
Residue:
291
Sequence:
MEFSRPPLVHVKGIPLIKYFAETIGPLQNFTAWPDDLLISTYPKSGTTWMSEILDMIYQGGKLEKCGRAPIYARVPFLEFKCPGVPSGLETLEETPAPRLLKTHLPLSLLPQSLLDQKVKVIYIARNAKDVVVSYYNFYNMAKLHPDPGTWDSFLENFMDGEVSYGSWYQHVKEWWELRHTHPVLYLFYEDIKENPKREIKKILEFLGRSLPEETVDSIVHHTSFKKMKENCMTNYTTIPTEIMDHNVSPFMRKGTTGDWKNTFTVAQNERFDAHYAKTMTDCDFKFRCEL
  
Inhibitor
Name:
BDBM23420
Synonyms:
7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one | CHEMBL8145 | Daidzein | US8552057, 7
Type:
isoflavone
Emp. Form.:
C15H10O4
Mol. Mass.:
254.2375
SMILES:
Oc1ccc(cc1)-c1coc2cc(O)ccc2c1=O
Structure:
Search PDB for entries with ligand similarity: