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Target
Sulfotransferase 1A1
Ligand
BDBM7460
Substrate
n/a
Meas. Tech.
ChEMBL_2281002
IC50
290±n/a nM
Citation
 Tanwar, AK; Dhiman, N; Kumar, A; Jaitak, V Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. Eur J Med Chem 213:0 (2021) [PubMed] 
Target
Name:
Sulfotransferase 1A1
Synonyms:
2.8.2.1 | ASTIV | Aryl sulfotransferase | Aryl sulfotransferase IV | Minoxidil sulfotransferase | Mx-ST | PST-1 | Phenol sulfotransferase | ST1A1 | St1a1 | Sulfokinase | Sulfotransferase 1A1 | Sult1a1 | Tyrosine-ester sulfotransferase
Type:
PROTEIN
Mol. Mass.:
33907.66
Organism:
Rat
Description:
ChEMBL_10115
Residue:
291
Sequence:
MEFSRPPLVHVKGIPLIKYFAETIGPLQNFTAWPDDLLISTYPKSGTTWMSEILDMIYQGGKLEKCGRAPIYARVPFLEFKCPGVPSGLETLEETPAPRLLKTHLPLSLLPQSLLDQKVKVIYIARNAKDVVVSYYNFYNMAKLHPDPGTWDSFLENFMDGEVSYGSWYQHVKEWWELRHTHPVLYLFYEDIKENPKREIKKILEFLGRSLPEETVDSIVHHTSFKKMKENCMTNYTTIPTEIMDHNVSPFMRKGTTGDWKNTFTVAQNERFDAHYAKTMTDCDFKFRCEL
  
Inhibitor
Name:
BDBM7460
Synonyms:
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromen-4-one | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;hydrate | CHEMBL50 | Quercetin | Quercetin (10) | Quercetin (21) | Quercetin (Qur) | US11021454, Compound Quercetin | US9180183, Quercetin | med.21724, Compound 4
Type:
Small organic molecule
Emp. Form.:
C15H10O7
Mol. Mass.:
302.2357
SMILES:
Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Structure:
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