Reaction Details Report a problem with these data
Target
Sulfotransferase 2A1
Ligand
BDBM19459
Substrate
n/a
Meas. Tech.
ChEMBL_2281003
IC50
34000±n/a nM
Citation
 Tanwar, AK; Dhiman, N; Kumar, A; Jaitak, V Engagement of phytoestrogens in breast cancer suppression: Structural classification and mechanistic approach. Eur J Med Chem 213:0 (2021) [PubMed] 
Target
Name:
Sulfotransferase 2A1
Synonyms:
2.8.2.14 | 2.8.2.2 | Bile salt sulfotransferase | Hydroxysteroid sulfotransferase | ST-20 | ST2A1 | St2a1 | Sulfotransferase 2A1 | Sult2a1
Type:
PROTEIN
Mol. Mass.:
33139.75
Organism:
Rat
Description:
ChEMBL_17057
Residue:
284
Sequence:
MPDYTWFEGIPFHAFGISKETLQNVCNKFVVKDEDLILLAYPKSGTNWLIEIVCLIQTKGDPKWIQSVTIWDRSPWIETDLGYDMLIKKKGPRLITSHLPMHLFSKSLFSSKAKVIYLVRNPRDVLVSGYYFWGNSTLAKKPDSLGTYVEWFLKGNVLYGSWFEHIRAWLSMREWDNFLLLYYEDMKKDTMGTIKKICDFLGKKLEPDELDLVLKYSSFQVMKENDMSNYSLLMKKSIFTGIGLMRKGTVGDWKNHFTVSQAEAFDKVFQEKMAGFPPGMFPWE
  
Inhibitor
Name:
BDBM19459
Synonyms:
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one | CHEMBL44 | Genistein | Genistein, 8 | Genisteol | Prunetol | US8552057, 2 | cid_5280961
Type:
Phytoestrogen
Emp. Form.:
C15H10O5
Mol. Mass.:
270.2369
SMILES:
Oc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O
Structure:
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