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Target
Stimulator of interferon genes protein
Ligand
BDBM453551
Substrate
n/a
Meas. Tech.
ChEMBL_2310370
EC50
>200000±n/a nM
Citation
 Shan, B; Hou, H; Zhang, K; Li, R; Shen, C; Chen, Z; Xu, P; Cui, R; Su, Z; Zhang, C; Yang, R; Zhou, G; Liu, Y; Guo, H; Chen, K; Fu, W; Jiang, H; Zhang, S; Zheng, M Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists. J Med Chem 66:3327-3347 (2023) [PubMed] 
Target
Name:
Stimulator of interferon genes protein
Synonyms:
STING_MOUSE | Endoplasmic reticulum interferon stimulator | MMITA | Mediator of IRF3 activation | Sting1 | Stimulator of interferon genes protein | Eris | Synonyms=Eris | Mita | Transmembrane protein 173 | mSTING | Mpys | Sting | Tmem173
Type:
PROTEIN
Mol. Mass.:
42834.49
Organism:
Mouse
Description:
ChEMBL_119061
Residue:
378
Sequence:
MPYSNLHPAIPRPRGHRSKYVALIFLVASLMILWVAKDPPNHTLKYLALHLASHELGLLLKNLCCLAEELCHVQSRYQGSYWKAVRACLGCPIHCMAMILLSSYFYFLQNTADIYLSWMFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILPGLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENGQPAGVCILEYATPLQTLFAMSQDAKAGFSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPSVLSQEPRLLISGMDQPLPLRTDLI
  
Inhibitor
Name:
BDBM453551
Synonyms:
4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutanoic acid | US10730849, Example 16
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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