Reaction Details Report a problem with these data
Target
Sigma intracellular receptor 2
Ligand
BDBM50534287
Substrate
n/a
Meas. Tech.
ChEMBL_2315617
IC50
418±n/a nM
Citation
 Straub, CJ; Rusali, LE; Kremiller, KM; Riley, AP What We Have Gained from Ibogaine: α3β4 Nicotinic Acetylcholine Receptor Inhibitors as Treatments for Substance Use Disorders. J Med Chem 66:107-121 (2023) [PubMed] 
Target
Name:
Sigma intracellular receptor 2
Synonyms:
Meningioma-associated protein 30 | Sigma-2 receptor | Sigma2 receptor | Transmembrane protein 97 | SGMR2_HUMAN | TMEM97 | MAC30 | S2R
Type:
Protein
Mol. Mass.:
20857.20
Organism:
Human
Description:
Q5BJF2
Residue:
176
Sequence:
MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
  
Inhibitor
Name:
BDBM50534287
Synonyms:
CHEMBL4519018
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: