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Target
Neurotensin receptor type 1
Ligand
BDBM50618615
Substrate
n/a
Meas. Tech.
ChEMBL_2317105
Kd
5.7±n/a nM
Citation
 Kühl, T; Georgieva, MG; Hübner, H; Lazarova, M; Vogel, M; Haas, B; Peeva, MI; Balacheva, AA; Bogdanov, IP; Milella, L; Ponticelli, M; Garev, T; Faraone, I; Detcheva, R; Minchev, B; Petkova-Kirova, P; Tancheva, L; Kalfin, R; Atanasov, AG; Antonov, L; Pajpanova, TI; Kirilov, K; Gastreich, M; Gmeiner, P; Imhof, D; Tzvetkov, NT Neurotensin(8-13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's disease. Eur J Med Chem 254:0 (2023) [PubMed] 
Target
Name:
Neurotensin receptor type 1
Synonyms:
neurotensin receptor type 1 | Neurotensin receptor 1 | NTR1_HUMAN | NTSR1 | NTRR | Dopamine receptor D2L/neurotensin receptor NTS1
Type:
PROTEIN
Mol. Mass.:
46278.89
Organism:
Human
Description:
ChEMBL_1453811
Residue:
418
Sequence:
MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY
  
Inhibitor
Name:
BDBM50618615
Synonyms:
CHEMBL1170627
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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