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Target
D(1A) dopamine receptor
Ligand
BDBM55121
Substrate
n/a
Meas. Tech.
ChEMBL_2325142
EC50
2.6±n/a nM
Citation
 Namballa, HK; Dorogan, M; Gudipally, AR; Okafor, S; Gadhiya, S; Harding, WW Discovery of Selective Dopamine Receptor Ligands Derived from (-)-Stepholidine via C-3 Alkoxylation and C-3/C-9 Dialkoxylation. J Med Chem 66:10060-10079 (2023) [PubMed] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | DRD1_HUMAN | DRD1
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Human
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM55121
Synonyms:
cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride | 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride | MLS000069419 | 3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)pyrocatechol;hydrochloride | US20240415800, Compound 2-7 (Dopamine)
Type:
Small organic molecule
Emp. Form.:
C8H11NO2
Mol. Mass.:
153.08
SMILES:
c1cc(c(cc1CCN)O)O
Structure:
Search PDB for entries with ligand similarity: