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Target
Motilin receptor
Ligand
BDBM50214265
Substrate
n/a
Meas. Tech.
ChEMBL_447562 (CHEMBL896576)
Ki
342±n/a nM
Citation
 Marsault, E; Benakli, K; Beaubien, S; Saint-Louis, C; Déziel, R; Fraser, G Potent macrocyclic antagonists to the motilin receptor presenting novel unnatural amino acids. Bioorg Med Chem Lett 17:4187-90 (2007) [PubMed]  Article 
Target
Name:
Motilin receptor
Synonyms:
G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN
Type:
PROTEIN
Mol. Mass.:
45365.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_122664
Residue:
412
Sequence:
MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
  
Inhibitor
Name:
BDBM50214265
Synonyms:
(5R,8R,11S)-11-(2-aminoethyl)-5-[(4-hydroxyphenyl)methyl]-8-(propan-2-yl)-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-1,4,7,10,13-benzoxatetrazacyclooctadecine-6,9,12-trione | CHEMBL232342
Type:
Small organic molecule
Emp. Form.:
C29H41N5O5
Mol. Mass.:
539.6663
SMILES:
CC(C)[C@H]1NC(=O)[C@@H](Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC(=O)[C@H](CCN)NC1=O
Structure:
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