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Target
D(3) dopamine receptor
Ligand
BDBM50116766
Substrate
n/a
Meas. Tech.
ChEMBL_2375715
Ki
0.500000±n/a nM
Citation
 Niu, ZX; Wang, YT; Zhang, SN; Li, Y; Chen, XB; Wang, SQ; Liu, HM Application and synthesis of thiazole ring in clinically approved drugs. Eur J Med Chem 250:0 (2023) [PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
Dopamine D3 receptor | DRD3_HUMAN | DRD3
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Human
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50116766
Synonyms:
(6S)-N(6)-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine | CHEMBL301265 | (-)-Pramipexole | 2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N(sup 6)-propyl-, (S)- | PRAMIPEXOLE | cid_119570
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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