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Target
D(1A) dopamine receptor
Ligand
BDBM50221663
Substrate
n/a
Meas. Tech.
ChEMBL_449680 (CHEMBL898784)
Ki
16000±n/a nM
Citation
 Rodriguez Loaiza, P; Löber, S; Hübner, H; Gmeiner, P Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes. Bioorg Med Chem 15:7248-57 (2007) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50221663
Synonyms:
CHEMBL241424 | N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-4-phenylethynylbenzamide
Type:
Small organic molecule
Emp. Form.:
C30H33N3O2
Mol. Mass.:
467.6019
SMILES:
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)C#Cc2ccccc2)CC1
Structure:
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