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Target
Oxytocin receptor
Ligand
BDBM50222060
Substrate
n/a
Meas. Tech.
ChEMBL_449794 (CHEMBL898900)
IC50
1000±n/a nM
Citation
 Molinari, AJ; Trybulski, EJ; Bagli, J; Croce, S; Considine, J; Qi, J; Ali, K; Demaio, W; Lihotz, L; Cochran, D Identification and synthesis of major metabolites of Vasopressin V2-receptor agonist WAY-151932, and antagonist, Lixivaptan. Bioorg Med Chem Lett 17:5796-800 (2007) [PubMed]  Article 
Target
Name:
Oxytocin receptor
Synonyms:
OT-R | OXTR | OXYR_HUMAN | Oxytocin
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42793.26
Organism:
Human
Description:
Oxytocin OXTR HEK293::B2R9L7
Residue:
389
Sequence:
MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA
  
Inhibitor
Name:
BDBM50222060
Synonyms:
1-(2-(2-chloro-4-(5-fluoro-2-methylbenzamido)benzamido)benzyl)-1H-pyrrole-2-carboxylic acid | CHEMBL238206
Type:
Small organic molecule
Emp. Form.:
C27H21ClFN3O4
Mol. Mass.:
505.925
SMILES:
Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)Nc2ccccc2Cn2cccc2C(O)=O)c(Cl)c1
Structure:
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