Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50639974
Substrate
n/a
Meas. Tech.
ChEMBL_2445929
EC50
7.7±n/a nM
Citation
 Pradhan, B; Pavan, M; Fisher, CL; Salmaso, V; Wan, TC; Keyes, RF; Rollison, N; Suresh, RR; Kumar, TS; Gao, ZG; Smith, BC; Auchampach, JA; Jacobson, KA Lipid Trolling to Optimize A3 Adenosine Receptor-Positive Allosteric Modulators (PAMs). J Med Chem 67:12221-12247[PubMed] 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | Adenosine A3 receptor (A3AR) | AA3R_HUMAN | ADORA3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Human
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50639974
Synonyms:
CHEMBL5565378
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: