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Target
D(1A) dopamine receptor
Ligand
BDBM50336863
Substrate
n/a
Meas. Tech.
ChEMBL_2446904
Ki
0.830000±n/a nM
Citation
 Dorogan, M; Namballa, HK; Harding, WW Natural Product-Inspired Dopamine Receptor Ligands. J Med Chem 67:12463-12484[PubMed] 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | DRD1_HUMAN | DRD1
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Human
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50336863
Synonyms:
(R)-6-ethyl-2-(2-fluoroethoxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol | CHEMBL1672312
Type:
Small organic molecule
Emp. Form.:
C20H22FNO2
Mol. Mass.:
n/a
SMILES:
CCN1CCc2cc(OCCF)cc-3c2[C@H]1Cc1cccc(O)c-31 |r|
Structure:
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