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Target
D(2) dopamine receptor
Ligand
BDBM50426497
Substrate
n/a
Meas. Tech.
ChEMBL_2446905
Ki
0.360000±n/a nM
Citation
 Dorogan, M; Namballa, HK; Harding, WW Natural Product-Inspired Dopamine Receptor Ligands. J Med Chem 67:12463-12484[PubMed] 
Target
Name:
D(2) dopamine receptor
Synonyms:
DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Human
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50426497
Synonyms:
FCE-21336 | Dostinex | CABERGOLINE
Type:
Small organic molecule
Emp. Form.:
C26H37N5O2
Mol. Mass.:
451.6
SMILES:
CCNC(=O)N(CCCN(C)C)C(=O)[C@@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(CC=C)C1 |r|
Structure:
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