Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50002316
Substrate
n/a
Meas. Tech.
ChEMBL_2446906
Ki
3.0±n/a nM
Citation
 Dorogan, M; Namballa, HK; Harding, WW Natural Product-Inspired Dopamine Receptor Ligands. J Med Chem 67:12463-12484[PubMed] 
Target
Name:
D(3) dopamine receptor
Synonyms:
Dopamine D3 receptor | DRD3_HUMAN | DRD3
Type:
PROTEIN
Mol. Mass.:
44213.40
Organism:
Human
Description:
ChEMBL_105671
Residue:
400
Sequence:
MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50002316
Synonyms:
LARODOPA | SINEMET | 4-(2-Amino-ethyl)-benzene-1,2-diol(DA) | CHEMBL59 | 4-(2-Amino-ethyl)-benzene-1,2-diol (dopamine) | PARCOPA | BENDOPA | (dopamine)4-(2-Amino-ethyl)-benzene-1,2-diol | 4-(2-Amino-ethyl)-benzene-1,2-diol | DOPAMINE4-(2-Amino-ethyl)-benzene-1,2-diol | INTROPIN | 4-(2-aminoethyl)benzene-1,2-diol | CARBILEV | DOPAR | 4-(2-Amino-ethyl)-benzene-1,2-diol( Dopamine) | 4-(2-Amino-ethyl)-benzene-1,2-diol (DA) | DOPAMINE
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
c1cc(c(cc1CCN)O)O
Structure:
Search PDB for entries with ligand similarity: