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Target
Calnexin
Ligand
BDBM50652793
Substrate
n/a
Meas. Tech.
ChEMBL_2514210
Kd
9625±n/a nM
Citation
 Tröster, A; Heinzlmeir, S; Berger, BT; Gande, SL; Saxena, K; Sreeramulu, S; Linhard, V; Nasiri, AH; Bolte, M; Müller, S; Kuster, B; Médard, G; Kudlinzki, D; Schwalbe, H NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family. ChemMedChem 13:1629-1633[PubMed] 
Target
Name:
Calnexin
Synonyms:
IP90 | Major histocompatibility complex class I antigen-binding protein p88 | p90 | CALX_HUMAN | CANX
Type:
PROTEIN
Mol. Mass.:
67509.54
Organism:
Human
Description:
ChEMBL_70497
Residue:
592
Sequence:
MEGKWLLCMLLVLGTAIVEAHDGHDDDVIDIEDDLDDVIEEVEDSKPDTTAPPSSPKVTYKAPVPTGEVYFADSFDRGTLSGWILSKAKKDDTDDEIAKYDGKWEVEEMKESKLPGDKGLVLMSRAKHHAISAKLNKPFLFDTKPLIVQYEVNFQNGIECGGAYVKLLSKTPELNLDQFHDKTPYTIMFGPDKCGEDYKLHFIFRHKNPKTGIYEEKHAKRPDADLKTYFTDKKTHLYTLILNPDNSFEILVDQSVVNSGNLLNDMTPPVNPSREIEDPEDRKPEDWDERPKIPDPEAVKPDDWDEDAPAKIPDEEATKPEGWLDDEPEYVPDPDAEKPEDWDEDMDGEWEAPQIANPRCESAPGCGVWQRPVIDNPNYKGKWKPPMIDNPSYQGIWKPRKIPNPDFFEDLEPFRMTPFSAIGLELWSMTSDIFFDNFIICADRRIVDDWANDGWGLKKAADGAAEPGVVGQMIEAAEERPWLWVVYILTVALPVFLVILFCCSGKKQTSGMEYKKTDAPQPDVKEEEEEKEEEKDKGDEEEEGEEKLEEKQKSDAEEDGGTVSQEEEDRKPKAEEDEILNRSPRNRKPRRE
  
Inhibitor
Name:
BDBM50652793
Synonyms:
CHEMBL5653589
Type:
Small organic molecule
Emp. Form.:
C26H20F3N7O
Mol. Mass.:
503.49
SMILES:
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2nn(C)cc12
Structure:
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