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Target
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Ligand
BDBM50652792
Substrate
n/a
Meas. Tech.
ChEMBL_2515152
Kd
8276±n/a nM
Citation
 Tröster, A; Heinzlmeir, S; Berger, BT; Gande, SL; Saxena, K; Sreeramulu, S; Linhard, V; Nasiri, AH; Bolte, M; Müller, S; Kuster, B; Médard, G; Kudlinzki, D; Schwalbe, H NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family. ChemMedChem 13:1629-1633[PubMed] 
Target
Name:
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1
Synonyms:
CBP | Csk-binding protein | PAG | PAG1 | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | Transmembrane adapter protein PAG | Transmembrane phosphoprotein Cbp
Type:
PROTEIN
Mol. Mass.:
46948.80
Organism:
Homo sapiens
Description:
ChEMBL_122851
Residue:
432
Sequence:
MGPAGSLLGSGQMQITLWGSLAAVAIFFVITFLIFLCSSCDREKKPRQHSGDHENLMNVPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCMQHYEEVQTSASDLLDSQDSTGKPKCHQSRELPRIPPESAVDTMLTARSVDGDQGLGMEGPYEVLKDSSSQENMVEDCLYETVKEIKEVAAAAHLEKGHSGKAKSTSASKELPGPQTEGKAEFAEYASVDRNKKCRQSVNVESILGNSCDPEEEAPPPVPVKLLDENENLQEKEGGEAEESATDTTSETNKRFSSLSYKSREEDPTLTEEEISAMYSSVNKPGQLVNKSGQSLTVPESTYTSIQGDPQRSPSSCNDLYATVKDFEKTPNSTLPPAGRPSEEPEPDYEAIQTLNREEEKATLGTNGHHGLVPKENDYESISDLQQGRDITRL
  
Inhibitor
Name:
BDBM50652792
Synonyms:
CHEMBL3752910
Type:
Small organic molecule
Emp. Form.:
C26H20F3N7O
Mol. Mass.:
503.49
SMILES:
Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1nc(-c2cccnc2)nc2c1cnn2C
Structure:
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