Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM10849
Substrate
n/a
Meas. Tech.
ChEMBL_484486 (CHEMBL1014012)
Ki
32500±n/a nM
Citation
 Schumacher, B; Scholle, S; Hölzl, J; Khudeir, N; Hess, S; Müller, CE Lignans isolated from valerian: identification and characterization of a new olivil derivative with partial agonistic activity at A(1) adenosine receptors. J Nat Prod 65:1479-85 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
ADENOSINE A2a | Rat striatal adenosine A2a receptor | Adenosine A2a receptor (A2a) | Adenosine receptors A2a | AA2AR_RAT | Adora2a | Adenosine receptor A2a and A3 | Adenosine Receptors A2a (A2a) | Adenosine A2 receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
45015.65
Organism:
Rat
Description:
Rat A2A receptors expressed in CHO cells.
Residue:
410
Sequence:
MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKGIIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAFVLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRTHVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGLGGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
  
Inhibitor
Name:
BDBM10849
Synonyms:
CHEMBL113 | 1,3,7-trimethyl-3,7-dihydropurine-2,6-dione | 1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione | Caffeine (1,3,7-trimethylxanthine) | caffeine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: