Reaction Details Report a problem with these data
Target
Thymidine kinase
Ligand
BDBM1
Substrate
n/a
Meas. Tech.
ChEMBL_490039 (CHEMBL987377)
Ki
257000±n/a nM
Citation
 Sandrini, MP; Shannon, O; Clausen, AR; Björck, L; Piskur, J Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria. Antimicrob Agents Chemother 51:2726-32 (2007) [PubMed]  Article 
Target
Name:
Thymidine kinase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
22211.58
Organism:
Staphylococcus aureus
Description:
ChEMBL_490039
Residue:
199
Sequence:
MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKPAIDDRYHKEKVVSHNGNAIEAINISKASEIMTHDLTNVDVIGIDEVQFFDDEIVSIVEKLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLINGKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL
  
Inhibitor
Name:
BDBM1
Synonyms:
dT | thymidine
Type:
Nucleoside or nucleotide
Emp. Form.:
C10H14N2O5
Mol. Mass.:
242.2286
SMILES:
Cc1cn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)[nH]c1=O
Structure:
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